POLYMER GENOMICS
The material channel of the genome — stacking energy, curvature, flexibility, groove geometry — computed at base-pair resolution and cross-indexed with 50 genomic layers. Queryable by humans and by agents.
The central dogma describes how sequence information flows between biopolymers — DNA to RNA to protein — and the asymmetries that constrain that flow. It is correct as far as it goes. Its scope, however, is sequence; the molecule carrying those sequences is also a physical object, and the dogma is silent on that channel.
DNA is a heteropolymer: a chain of monomers with position-dependent physical-chemical properties. Every base-pair step has a stacking energy, a melting temperature, an intrinsic curvature, a flexibility. An AT-rich region and a GC-rich region are, in the language of polymer physics, different materials.
That gives two information channels on one molecule. The symbolic channel maps codons, motifs, and recognition sites to discrete decoded outcomes — localized in the genome, decoder-dependent. The material channel maps sequence to a continuous energy surface — self-executing, present across the entire genome, physically prior to the genetic code by billions of years. This site computes the second one.
Under active construction. New layers and tools added continuously. A full elaboration of the theoretical framework is in preparation.